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Description

Free fatty acids from either adipose tissue (fat), or from the conversion of excess carbohydrate intake, accumulate in the liver cell resulting in oxidative stress, inflammation, and liver injury

Bass J, Takahashi JS

In this reaction, selenite reacts with glutathione (GSH), forming GS-Se-SG, which is then reduced by NADPH and GSH reductase to the unstable intermediate GS-Se