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Rapamycin complex 1 (mTORC1) is a highly conserved regulator of cell growth and is one of the most integrated signaling nodes in all cells

PMID: 40712560 Nat Cancer Discovering the anti-cancer potential of non-oncology drugs by systematic viability profiling

e , Representative FRAP images (left) and fluorescence recovery curves (right) of mEm-TDP-43 in control and PML-KO HEK293T cells

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The authors reported a 55.8% reduction in facial wrinkle volume and a 32.8% reduction in wrinkle depth compared with control serum, alongside in vitro evidence that GHK-Cu increased both collagen and elastin production in human dermal fibroblasts at concentrations as low as 0.01 nM [4]