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Specifically, -hydroxybutyrate has been shown to inhibit the NLRP3 inflammasome, resulting in decreased IL-1 and IL-18 production in human monocytes and in murine models [53]

[DOI] [PubMed] [Google Scholar] 28.Double-blind, placebo-controlled study of entacapone in levodopa-treated patients with stable Parkinson disease

doi: 10.1517/14712598.2014.918099

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[135] For studies that did not conduct randomization on either patients or SVGs, confounders could further undermine external validity of the findings

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