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Notwithstanding these difficulties, the integration of data with investigations might improve the knowledge of the therapeutic possibilities of a molecule [103, 104]

(2021a, b) in diabetic db/db mice and high glucose-induced HK-2 cells, AC could improve early renal damage induced by DM through regulating TGF-/Smad signaling pathway, which is implicated in regulating renal fibrosis in chronic kidney disease (Wang et al

The analytical column was placed inside the Column Toaster (Bruker) and its emitter side was installed inside the CaptiveSpray ion source (Bruker) according to the manufacturer instructions with the column temperature set to 50 C