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These data implicate the tubulin protein family as primary targets of 4-HNE adduction in the oocyte, a result that was subsequently confirmed via immunoprecipitation of -, -, and -tubulin from H 2 O 2 -treated GV and MII oocyte lysates

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doi: 10.1111/j.1939-1676.2010.0584.x, 99