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Description

Metastatic cells show increased levels of reactive oxygen species, alterations in amino acid metabolism, and changes in ATP and the tricarboxylic acid (TCA) cycle that reflect metabolic adaptions [67, 68]

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the medications are not controlled substances and all other requirements of this section are met

While direct quantification of oxidant species in the body would be ideal for assessing oxidative stress, it is not feasible due to their high reactivity, short half-life, and the challenges of quantification using conventional techniques