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4.4 Relationship between GSH modulation and cognitive performance In young adults, an increase of GSH in IFC and IPL (from resting state MRS to fMRS) predicted a better cognitive performance

Treating the metabolic syndrome by fecal transplantationcurrent status

Watase, K

T.FahnS.Martinez-MartinP.et al

NADPH is a critical reductant produced during immune metabolism, maintaining the function of intracellular antioxidant systems (e.g., thioredoxin and glutathione systems) and bidirectionally regulating ROS production and clearance in certain cells such as macrophages 143,144,145,146

These enzymes not only maintain basal metabolic flux through their catalytic activity but also participate in epigenetic regulation, transcription factor activation, redox homeostasis, and the modulation of cell death pathways, thereby acting as upstream drivers of mitochondrial metabolic reprogramming [95]