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Similarly, combined analysis of the 165 ROS-associated genes with the 3352 downregulated DEGs revealed 22 candidate ROS-associated downregulated DEGs in COAD, including LRPK2, TLR6, CYBB, ATP7A, HIF1A, CD36, CYP1B1, P2RX7, NOX4, TLR2, SH3PXD2A, BCL2, AGTR1, FBLN5, PDK4, THBS1, ITGAM, PDGFRB, EDN1, LEP, SFTPD, and MAPT

Mitochondrial dysfunction reduces the energy available to the immune system and impairs the immune systems ability to keep the gut microbiota under control

Group-V: HFD and nicotine (1.5 mg/kg, b.wt, I.P) (Sinha-Hikim AP, et al ., 2017)+Vitamin-U (100 mg/kg, b.wt) (Sokmen BB, et al ., 2012)+Vitamin E (200 mg/kg, b.wt, oral) (Oliveira CP, et al ., 2003)

Post-translational oxidative modifications of hemostasis proteins: structure, function, and regulation

2014;16:ii6ii

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