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Notably, Akt phosphorylation in Insr P1195L/ +/HFD mice was barely induced by insulin, indicating that insulin signaling is markedly impaired by combination of genetic mutation ( Insr P1195L ) in the insulin receptor and environmental condition (HFD feeding) in both WAT and liver

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For diagnostic purposes, PET radionuclides like 68 Ga, 64 Cu, and SPECT radionuclides like 99m Tc and 111 In, are commonly used

Mix well and store in a closed container