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Criteria used to exclude ineligible papers were: studies published in language other than English, comments, personal opinions, old data, not relevant to the topic, no quantifiable evidence, non-relevant population and outcome

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Moreover, the clinical translation of pharmacological agents targeting mitochondrial function and energy metabolism remains limited, highlighting the need for further investigation in both preclinical and clinical settings

A high-conductance mode of a poly-3-hydroxybutyrate/calcium/polyphosphate channel isolated from competent Escherichia coli cells