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Carey and Pickarts ultrasound study found an average increase in collagen density of ~28% at 12 weeks, with top responders reaching 51%

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Read review Dihexa for Migraine & Chronic Migraine The May 2024 NICE TA973 atogepant (Aquipta, AbbVie) approval, the rimegepant / erenumab / galcanezumab / fremanezumab / eptinezumab CGRP pathway, 2025 chronic-migraine hippocampal atrophy & accelerated brain ageing research, the Tanure BDNF-elevated-in-attack paradox, NICE NG150, and the ~10 million UK migraine population

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