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Labels such as psychogenic or psychosomatic are applied by doctors, in part, because of a statistical correlation with higher levels of depression and anxiety.[ref] However, the physiological and cellular changes in people with chemical sensitivities are measurable, statistically significant, and visible, strongly suggesting a physiological cause rather than a psychological cause.[ref][ref] On the other hand, there are several clinical trials using specific solvents or chemical odors that found no statistical change in measured parameters (e.g

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Exp Dermatol 27(2):115123 Kryczek I, Bruce AT, Gudjonsson JE, Johnston A, Aphale A, Vatan L, Szeliga W, Wang Y, Liu Y, Welling TH (2008) Induction of IL-17+ T cell trafficking and development by IFN-: mechanism and pathological relevance in psoriasis