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doi:10.1111/j.1471-4159.2006.03693.x PMID: 16539679 4

For long-term use, it is especially important to have medical oversight and guidance

And its not because of any magic its because these are natural substances that our bodies make and are familiar with, so thats what gives them this incredible safety profile. The FDA, however, has publicly stated that there is not enough evidence from human clinical trials on the safety or efficacy of these drugs

Many protocols explore 2,0002,500 mcg twice weekly for a loading phase of 46 weeks, followed by a reduced maintenance frequency

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