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The authors acknowledge the use of ChatGPT (OpenAI, San Francisco, CA, USA) as an AI-assisted language editing tool for grammar correction, sentence restructuring and improvement of fluency during manuscript preparation

On the other hand, the activation of ACE2 receptors limits activated microglia polarization to the M1 phenotype and shifts its polarization to the M2 anti-inflammatory phenotype [355], which demonstrates the critical role of the renin-angiotensin system (RAS) in neuroinflammation

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These injections usually use short, very thin needles, and dont cause much discomfort