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Pharmacists must be aware of the contraindications, special warnings and precautions and ensure patients: Do not have risk factors for venous thromboembolism (see Box 2)

BAs act in the brain by interacting with key receptors on neurons and glial cells-Farnesoid X receptor (FXR), Takeda G protein receptor 5 (TGR5), GR, and sphingosine-1-phosphate receptor 2 (S1PR2