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Theranostics 15 (8), 3424 (2025)

The other hypothesis suggested that a K + channel protein is the oxygen sensor and inhibition of this channel and the ensuing depolarization is the initial event in transduction, as indicated by Peers and Kemp [1]

Second, a substantial portion of evidence comes from animal models, which may not fully reflect human physiological responses [17]

Hamal, C

14-hydroxy-11-methoxy-10-(2-methoxypropoxy)-4,6a,6b, 12,14b-pentamethyl-8a-(methylamino)-4-(1-(2,4,8-trimethyl-2,5,6,7,8,8a-hexahydro-1 H -pyrido [3,4-d1,3]oxazin-6-yloxy)ethyl)octadecahydro-1 H -phenanthro[1,2-h]isochromen-3(4 H )-one and 6-(17-(4,6-dihydroxy-5-methoxy-2-(methylperoxy)-tetrahydro-2H-pyran-3-yloxy)-1,12-di-methoxy-4,5,8,10,12,13,14,17-octahydro-1 H -cyclopenta[a]phenanthren-3-yloxy)-2-(methylper- oxy)-3,4-dihydro-2 H -pyran-3,4,5-triol have been obtained from the Jamun roots

CTEP Trial Development and Conduct - NCI