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These ten diseases accounted for over 50% of recent R&D activity in the rare disease field 14

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It works by increasing levels of dopamine and norepinephrine in the brain, which helps improve focus, attention, and impulse control in people with ADHD

Statistical analysis We utilized a mixed model analysis of variance for repeated measures to analyze daily variations in TST, each sleep stage (st1 + 2, st3 + 4, and stREM), and subjective and objective sleepiness measured by the visual analogue scale and Maintenance Wakefulness Test, respectively