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Featherstone RE, Kapur S, Fletcher PJ

The androgen receptor can use different transactivation domains (AF1 and AF5, respectively, in the NH 2 -terminal domain and AF2 in the COOH-terminal domain) depending on the "form" of the receptor protein [Figure 8, see above] (103)

For people with PCOS and severe insulin resistance, surgery can be particularly helpful because it often leads to major improvements in metabolic health