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Lu C, Perez-Soler R, Piperdi B, Walsh GL, Swisher SG , Smythe WR, Shin HJ, Ro JY, Feng L, Truong M, Yalamanchili A, Lopez-Berestein G, Hong WK, Khokhar AR, Shin DM

Studies confirm that conventional frozen semen prepared without cryoprotectants induces severe functional decline in spermatozoa due to oxidative damage and cold shock, markedly reducing both cleavage and blastocyst rates [44, 45]

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TABLE 1 Summary of DDS treatment methods for gout