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10.1038/s41419-023-06154-8 77 LiuW.YuM.XieD.WangL.YeC.ZhuQ.et al (2020b)

Secreted predominantly by the pineal gland, melatonin coordinates circadian rhythms and peaks during the night in healthy individuals

Steady-state operation enables regulation of microbial density through removal of unbound microbes, continuous nutrient supply, maintenance of stable pH, and clearance of microbial metabolic wastes, while preserving accurate oxygen gradients

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Research has shown that a biallelic poly (AT) insertion/deletion polymorphism in Intron 9 of XPC is associated with increased risk for skin, breast and prostate cancers, [12] [13] [14] especially in North Indian populations