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Much like a deep learning model that refines its accuracy through iteration, the future of herbal nanomedicine will depend on repeated cycles of formulation optimization, preclinical testing, and rigorous clinical trials

Funding The work of the authors work was supported by A*STAR Career Development Award (C210112047 to TML), pre-gap funding (I22D1AG050 to TML) and A*STAR Industry Alignment Fund Pre-Positioning (IAF-PP) (H18/01/a0/021 and H18/AH/a0/001)

6 Department of Thoracic Surgery, Yunfeng Hospital, Xuanwei City, Yunnan Province, Peoples Republic of China *These authors contributed equally to this work Abstract: COPD, characterized by long-term poorly irreversible airway limitation and persistent respiratory symptoms, has resulted in enormous challenges to human health worldwide, with increasing rates of prevalence, death, and disability

The reality is more nuanced: The critical difference is clinical validation depth

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doi:10.1038/nature12056