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2i) and increased lipid clearance from circulation (Fig

109 It remains unclear whether the protective effect of UAMC-3203 in the iron/APAP model is due to reduced LPO alone or its combination with the effect on Sab

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Significantly, the antimalarial potency of these compounds correlated well with their ability to disrupt erythrocyte redox balance in vitro (and slightly less strongly in vivo in mice), leading the authors to conclude that erythrocyte enolase is likely the common target that links these two characteristics