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Control + Rhodamine B (RB): Cells were treated with 1 M Rhodamine B in DMEM for 24 h under normoxic conditions

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The Nutrition Source

In humans, cyanocobalamin must undergo intracellular enzymatic conversion to the active coenzyme formsmethylcobalamin and adenosylcobalaminwhich, depending on the pH environment, can interconvert with hydroxocobalamin ( Despite extensive biochemical knowledge of cobalamin metabolism and its physiological importance, the optimal supplementation route for maintaining or restoring adequate vitamin B12 levels remains debated

Thus, specific biological effects can be induced by treatment with variants with limited function

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